Creatine is the most extensively researched supplement on earth. The science is settled. The dosing protocols, somehow, are not.

Roughly half the men I talk to who take creatine are taking it wrong. Either too little, at the wrong time, or in a form that the literature has long since identified as inferior. None of this is their fault. The supplement industry has spent thirty years confusing the issue.

Here's what the actual research supports.

The form: monohydrate, period

Creatine monohydrate is the form used in roughly 95% of all peer-reviewed studies. It's also the cheapest. Every other form (HCL, ethyl ester, "magnesium chelate") has either failed to outperform monohydrate in head-to-head trials, or has not been tested at all.

The marketing for "advanced" creatine forms is the supplement industry's attempt to charge a premium for an ingredient whose patent expired decades ago. Don't fall for it. A $20 tub of creatine monohydrate from a reputable brand is the right product.

The dose: 5 grams a day, every day, no loading

The "loading phase" (20 grams a day for a week, then dropping to 5 grams) is no longer the recommended protocol. It produces no faster results long-term and produces gastrointestinal distress short-term. Just take 5 grams a day from day one. Saturation occurs over 3–4 weeks regardless.

Take it whenever. The "must take post-workout" advice is largely marketing. The cumulative saturation matters. The timing of any individual dose does not.

The drinking water requirement

Creatine pulls water into muscle cells. This is part of how it works. It also means you need to drink more water than you would otherwise. About a half-gallon a day is the floor. The men who don't increase their water intake on creatine are the ones who report cramping. The men who do, don't.

What it does, what it doesn't

What creatine does: 5–15% improvement in maximal strength and power output. Slightly improved muscle hypertrophy when training is also dialed in. Possible cognitive benefits in older adults. Possibly mood-supportive in some research.

What creatine does not do: build muscle by itself, increase testosterone, "load" your body with energy, "cycle" out of your system in ways that require breaks. The "creatine cycling" protocols are unsupported by research.

For men over 40 specifically

The case for creatine after 40 is stronger than the case for creatine at any other age. Age-related muscle and cognitive decline are both partially mediated by the cellular pathways creatine supports. The men who supplement consistently from 40 onward retain more muscle and possibly more cognitive function than the men who don't.

It's $20 a month for the most reliably-supported supplement available. Most of what's said about it is wrong. The product itself works.